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50 积分 2024-09-23 加入
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update
6天前
已完结
Design and Characterization of a Pyridone-Containing EZH2 Inhibitor Phosphate Prodrug
25天前
已完结
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075
1个月前
已完结
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
1个月前
已完结
Global Prevalence and Incidence of Amyotrophic Lateral Sclerosis
1个月前
已完结
Discovery of HMPL-306 (Ranosidenib), a New Potent and Selective Dual Inhibitor of Mutant IDH1 and 2 in Clinical Development for Cancer Treatment
1个月前
已完结
The phospholipid kinase PIKFYVE is essential for Th17 differentiation
1个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
1个月前
已完结
Development of RMC-6236, a potent and orally bioavailable RAS(ON) multi-selective tri-complex inhibitor for the treatment of RAS-addicted cancers by targeting multiple RAS variants
1个月前
已关闭
Targeting common disease pathomechanisms to treat amyotrophic lateral sclerosis
1个月前
已完结
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