Lv4
630 积分 2022-06-29 加入
Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA
26天前
已完结
OS-030 Efficacy and safety of xalnesiran with and without an immunomodulator in virologically suppressed participants with chronic hepatitis B: end of study results from the phase 2, randomized, controlled, adaptive, open-label platform study (PIRANGA)
2个月前
已完结
WED-371 Imdusiran (AB-729) administered every 8 weeks in combination with 24 weeks of pegylated interferon alfa-2a in virally suppressed, HBeAg-negative subjects with chronic HBV infection leads to HBsAg loss in some subjects at end of IFN treatment
2个月前
已关闭
Safety and antiviral activity of short-duration combinations of the investigational small interfering ribonucleic acid VIR-2218 with the neutralizing, vaccinal monoclonal antibody VIR-3434: post-treatment follow-up from the Phase 2 MARCH trial
2个月前
已完结
Reduction of hepatitis B surface antigen mediated by RNA interference therapeutic AB-729 in chronic hepatitis B patients is associated with T cell activation and a decline in exhausted CD8 T cells
2个月前
已完结
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels
3个月前
已完结
The global burden of viral hepatitis: better estimates to guide hepatitis elimination efforts
3个月前
已完结
Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study
3个月前
已完结
Varied immune responses of HBV-specific B cells in patients undergoing pegylated interferon-alpha treatment for chronic hepatitis B
3个月前
已完结
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
3个月前
已完结
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