Lv31
376 积分 2024-04-06 加入
Advancing Target Validation and Ligandability Assessment: Fragment Screening via 19F NMR Spectroscopy
1天前
待确认
Advancing Target Validation and Ligandability Assessment: Fragment Screening via 19F NMR Spectroscopy
2天前
待确认
Precision by design: Surface plasmon resonance and the integration of biophysics in fragment-based drug discovery
3天前
已完结
Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity
14天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
15天前
已完结
Structure–Activity and Structure–Degradation Relationship Studies of 2-Amino-6-(benzimidazol-2-ylmethyl)-N9-heteroarylpurines as Potent and Selective CDK12/13 Inhibitors and Cyclin K Degraders
16天前
已完结
Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent “Type V” Kinase Inhibitors
16天前
已完结
Discovery of Potent and Brain-Penetrant Inverse Agonists for GPR61, an Orphan G Protein-Coupled Receptor
16天前
已完结
Protein–Small Molecule Interactions by WaterLOGSY
26天前
已完结
Structural basis for DCAF2 as a novel E3 ligase for PROTAC-mediated targeted protein degradation
28天前
已完结
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