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ZX612
Lv6
2950 积分
2023-06-20 加入
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Efficient Manufacturing Process for the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) via a Crystallization-Driven Diastereoselective Pictet–Spengler Condensation
2个月前
已完结
Axial Chirality in the Sotorasib Drug Substance, Part 1: Development of a Classical Resolution to Prepare an Atropisomerically Pure Sotorasib Intermediate
2个月前
已完结
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
2个月前
已完结
Development of a Practical Telescoped Process to Prepare (P)-7-(2-Amino-6-fluorophenyl)-4-hydroxy-6-(trifluoromethyl)pyrido[3,4-d]pyrimidin-8(7H)-one: a Key Intermediate of KRASG12C Inhibitor GH35
2个月前
已完结
Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 2: Synthesis of the Payload, Linker, and Drug Linker
2个月前
已完结
Development and Execution of a Scalable Route to an Immunology ADC Drug-Linker for ABBV-154
2个月前
已完结
First-Generation Process Development for the Synthesis of Baloxavir Marboxil: Early-Stage Development of Synthetic Methods to Prepare Baloxavir Marboxil Intermediates
2个月前
已完结
Stereoselective Synthesis of the IDO Inhibitor Navoximod
2个月前
已完结
Scalable Synthesis of ABBV-105 Enabled by Suzuki Coupling with Low Pd Loading, Ru-Catalyzed Asymmetric Hydrogenation, and Acylation Using Impinging Jet
2个月前
已完结
Development of a Directed Ketal Hydrogenation for the Synthesis of a Key Intermediate of Lanabecestat
2个月前
已完结
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感谢,速度真快
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