Lv51
1050 积分 2021-12-07 加入
Know your molecule: pharmacological characterization of drug candidates to enhance efficacy and reduce late-stage attrition
1个月前
已完结
First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy
1个月前
已完结
Harnessing conformational drivers in drug design
1个月前
已完结
Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474
1个月前
已完结
An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes
1个月前
已完结
Beyond Rule of Five and PROTACs in Modern Drug Discovery: Polarity Reducers, Chameleonicity, and the Evolving Physicochemical Landscape
2个月前
已完结
Photochemistry in Medicinal Chemistry and Chemical Biology
2个月前
已完结
Macrocyclization strategy for improving candidate profiles in medicinal chemistry
2个月前
已完结
The antibody–drug conjugate landscape
2个月前
已完结
The New Frontier: Merging Molecular Glue Degrader and Antibody–Drug Conjugate Modalities To Overcome Strategic Challenges
2个月前
已完结
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