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55 积分 2021-06-24 加入
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
1天前
待确认
Design, synthesis and anticancer evaluation of selective 2,4-disubstituted pyrimidine CDK9 inhibitors
3天前
已完结
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
12天前
已完结
Transcriptional regulation and therapeutic potential of cyclin-dependent kinase 9 (CDK9) in sarcoma
16天前
已完结
Cyclin-dependent kinases in DNA damage response
16天前
已完结
Poly (ADP-ribose) polymerase (PARP) inhibitors as anticancer agents: An outlook on clinical progress, synthetic strategies, biological activity, and structure-activity relationship
16天前
已完结
Design, synthesis, and biological evaluation of novel 4,4′-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer
17天前
已完结
Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma
21天前
已完结
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
27天前
已完结
Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch
1个月前
已完结
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