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70 积分 2021-03-11 加入
Ispinesib as an Effective Warhead for the Design of Autophagosome-Tethering Chimeras: Discovery of Potent Degraders of Nicotinamide Phosphoribosyltransferase (NAMPT)
3天前
已完结
Pharmacokinetic-Pharmacodynamic Characterization of the Cardiovascular, Hypnotic, EEG and Ventilatory Responses to Dexmedetomidine in the Rat
14天前
已关闭
Designing Chromane Derivatives as α2A-Adrenoceptor Selective Agonists via Conformation Constraint
1个月前
已完结
Rational modification of PROTACs for tumor-selective protein degradation
1个月前
已完结
Enrichment-Free, Targeted Covalent Drug Discovery in Live Cells
2个月前
已完结
VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation
2个月前
已完结
Discovery of Novel Potent Triple IKZF1/2/3 Degraders for the Treatment of Hematological Cancers
2个月前
已完结
Identification of an allosteric site on the E3 ligase adapter cereblon
2个月前
已完结
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects
3个月前
已完结
A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity**
3个月前
已完结