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40 积分 2023-11-07 加入
Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer
1天前
已完结
Property-based optimisation of PROTACs
1个月前
已完结
Hydrophobic tag tethering degrader as a promising paradigm of protein degradation: past, present and future perspectives
4个月前
已完结
Discovery of Potent and Selective c-Met Degraders for Hepatocellular Carcinoma Treatment
5个月前
已完结
Augmentation of the antitumor effects of PARP inhibitors in triple-negative breast cancer via degradation by hydrophobic tagging modulation
5个月前
已关闭
Discovery of a selective c-MET inhibitor with a novel binding mode
7个月前
已完结
Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression
9个月前
已完结
Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer
10个月前
已完结
Dual Microfluidic Sensor System for Enriched Electrochemical Profiling and Identification of Illicit Drugs On-Site
11个月前
已完结
Discovery of Highly Potent CRBN Ligands and Insight into Their Binding Mode through Molecular Docking and Molecular Dynamics Simulations
1年前
已完结
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