Lv71
4988 积分 2021-07-08 加入
Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases – where are we presently?
1小时前
已完结
Cedirogant Population Pharmacokinetics and Pharmacodynamic Analyses of Interleukin‐17A Inhibition in Two Phase I Studies in Healthy Participants and Participants with Moderate to Severe Psoriasis
6天前
已完结
RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer
6天前
已完结
Tumor‐derived exosomes induce immunosuppressive macrophages to foster intrahepatic cholangiocarcinoma progression
10天前
已完结
Property-based optimisation of PROTACs
12天前
已完结
GCN2 kinase activation by ATP-competitive kinase inhibitors
24天前
已完结
The importance of sulfur-containing motifs in drug design and discovery
24天前
已完结
Modes of action insights from the crystallographic structures of retinoic acid receptor-related orphan receptor-γt (RORγt)
25天前
已完结
Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity
25天前
已完结
Crystallographic landscape provides molecular insights into the modes of action of diverse ROR-γt modulators
25天前
已完结
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