Lv1
38 积分 2024-11-28 加入
Discovery of Novel Mcl-1 Inhibitors with a 3-Substituted-1H-indole-1-yl Moiety Binding to the P1–P3 Pockets to Induce Apoptosis in Acute Myeloid Leukemia Cells
7天前
已完结
Discovery of Novel Mcl1 Inhibitors with a 3Substituted1Hindole-1-yl Moiety Binding to the P1P3 Pockets to Induce Apoptosis in Acute Myeloid Leukemia Cells
7天前
已关闭
Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Fluorinated Candidates as PI3K Inhibitors: Targeting Fluorophilic Binding Sites
10天前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
11天前
已完结
Indolo[3,2-c]isoquinoline Hydroxamic Acid Derivatives as Novel Orally Topoisomerase-Histone Deacetylase Dual Inhibitors for NSCLC Therapy
3个月前
已完结
Discovery of Novel 5-Cyano-3-phenylindole-Based LSD1/HDAC Dual Inhibitors for Colorectal Cancer Treatment
3个月前
已完结
Discovery of a Novel Potent STAT3 Inhibitor HP590 with Dual p-Tyr705/Ser727 Inhibitory Activity for Gastric Cancer Treatment
4个月前
已完结
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells
4个月前
已完结
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