Lv6
3139 积分 2021-08-04 加入
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
10天前
已完结
Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
14天前
已完结
Antibody–Drug Conjugates for the Treatment of Non-Small Cell Lung Cancer with Central Nervous System Metastases
16天前
已完结
Pharmacologic restoration of GTP hydrolysis by mutant RAS
21天前
已完结
Pharmacologic restoration of GTP hydrolysis by mutant RAS
21天前
已关闭
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19
1个月前
已完结
Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors
1个月前
已完结
Macrocyclization strategy for improving candidate profiles in medicinal chemistry
1个月前
已完结
Development and validation of a sensitive UPLC–MS/MS analytical method for GFH009 in rat plasma and its application to toxicokinetics studies
1个月前
已完结
Design of Novel Series of Antimalarial PMX Inhibitors with Increased Half-Life via Molecular Property Optimization
1个月前
已完结
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