Lv4
670 积分 2023-09-25 加入
Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair
28天前
已完结
Closing the Design–Make–Test–Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability
28天前
已完结
Development of a Buchwald–Hartwig Amination for an Accelerated Library Synthesis of Cereblon Binders
1个月前
已完结
Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization
1个月前
已完结
Structural insight into selectivity of amylin and calcitonin receptor agonists
1个月前
已完结
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs
4个月前
已完结
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy
4个月前
已完结
Photoredox/Nickel Dual Catalysis-Enabled Cross-Dehydrogenative C–H Amination of Indoles with Unactivated Amine
5个月前
已完结
Discovery of a Novel Glucagon-like Peptide-1 (GLP-1) Analogue from Bullfrog and Investigation of Its Potential for Designing GLP-1-Based Multiagonists
6个月前
已完结
The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery
6个月前
已完结
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