Lv51
840 积分 2022-10-07 加入
Selective targeting of oncogenic hotspot mutations of the HER2 extracellular domain
7天前
已完结
Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders
18天前
已完结
Potent Inhibition and Rapid Photoactivation of Endogenous Bruton’s Tyrosine Kinase Activity in Native Cells via Opto-Covalent Modulators
1个月前
已完结
Lysosome Targeting Chimaeras for Glut1-Facilitated Targeted Protein Degradation
3个月前
已完结
Targeted Protein Degradation: Current and Emerging Approaches for E3 Ligase Deconvolution
4个月前
已完结
Genetically Encoded Epoxide Warhead for Precise and Versatile Covalent Targeting of Proteins
5个月前
已完结
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors
6个月前
已完结
Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2
7个月前
已完结
Proteome-scale discovery of protein degradation and stabilization effectors
7个月前
已完结
Mechanisms of regulating NIS transport to the cell membrane and redifferentiation therapy in thyroid cancer
8个月前
已完结
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