Lv74
4290 积分 2021-05-06 加入
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity
7小时前
待确认
Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα)
7小时前
待确认
Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
7小时前
待确认
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties
7小时前
待确认
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
7小时前
待确认
Degrader–Antibody Conjugates: Emerging New Modality
7小时前
待确认
Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates
7小时前
待确认
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody–Drug Conjugates
10小时前
待确认
Evaluation of Double Self-Immolative Linker-Based Antibody–Drug Conjugate FDA022-BB05 with Enhanced Therapeutic Potential
10小时前
待确认
Design and Evaluation of a Folate-Targeted PEG-MMAE Conjugate with Enzyme-Activated Drug Release for Enhanced Tumor Selectivity and Antitumor Efficacy
10小时前
待确认
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