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484 积分 2024-03-19 加入
Macrocyclization strategy for improving candidate profiles in medicinal chemistry
12天前
已完结
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead
16天前
已完结
A decade of piperazine-based small molecules approved by USFDA: Exploring the medicinal chemistry impact of this versatile pharmacophore
16天前
已完结
Exploring triazole-based drugs: Synthesis, application, FDA approvals, and clinical trial updates–A comprehensive review
16天前
已完结
Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
1个月前
已完结
Discovery of HMPL-306 (Ranosidenib), a New Potent and Selective Dual Inhibitor of Mutant IDH1 and 2 in Clinical Development for Cancer Treatment
1个月前
已完结
TCB-2 [(7R)-3-bromo-2, 5-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl]methanamine]: A hallucinogenic drug, a selective 5-HT2A receptor pharmacological tool, or none of the above?
1个月前
已关闭
Highlights on U.S. FDA-Approved Halogen-Containing Drugs in 2024
1个月前
已完结
A perspective on the application of macrocyclic design strategies in antitumor drugs
2个月前
已完结
Pyrimidine-based dual-target inhibitors targeting epidermal growth factor receptor for overcoming drug resistance in cancer therapy(2006-present)
2个月前
已完结
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