Lv1
34 积分 2024-10-22 加入
Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy
4天前
已完结
Discovery and Preclinical Evaluation of PBX-7016, a Methylenedioxy-Camptothecin Payload for Antibody-Drug Conjugates with Enhanced Therapeutic Potential
15天前
已完结
Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy
15天前
已完结
Ramantamig (JNJ-79635322), a novel T-cell-engaging trispecific antibody targeting BCMA, GPRC5D, and CD3, in multiple myeloma models
15天前
已完结
Pharmacological, computational, and mechanistic insights into triptolide’s role in targeting drug-resistant cancers
1个月前
已完结
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors
1个月前
已完结
HER3 upregulation reduces DS-8201 sensitivity in HER2-positive tumor cells by ATR/CHK1/FoxO1 signaling cascade
1个月前
已完结
IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer
2个月前
已完结
Preclinical development and characterisation of 99mTc-NM-01 for SPECT/CT imaging of human PD-L1
2个月前
已完结
Development and Characterization of a Lysosome-Targeting SLC3A2/PD-L1 Bispecific Antibody–Drug Conjugate for Enhanced Antitumor Efficacy in Solid Tumors
3个月前
已完结