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Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial
6天前
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TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC
7天前
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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
14天前
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Mdm2 promotes the rapid degradation of p53
14天前
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E1 Enzymes as Therapeutic Targets in Cancer
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A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment
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USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer
15天前
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USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ
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USP7 facilitates deubiquitination of LRRC42 in colorectal cancer to accelerate tumorigenesis and augment Wnt/β-catenin signaling
19天前
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The deubiquitinase USP44 enhances cisplatin chemosensitivity through stabilizing STUB1 to promote LRPPRC degradation in neuroblastoma
19天前
已完结
Older adults’ technology anxiety as a barrier to digital inclusion: a scoping review
1年前
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