Lv46
620 积分 2024-07-02 加入
Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity
15分钟前
已完结
Development of Tricyclic 4,5-Dihydro-3H-pyrrolo[2,3-c]quinolin-4-ones as Potent Autotaxin Inhibitors for Pulmonary Fibrosis Treatment In Vivo
2天前
已完结
Design, Biological Characterization, and Discovery of Capromorelin Derivatives as Oral Growth Hormone Secretagogue Receptor Type 1a Agonist for the Treatment of Growth Hormone Deficiency
2天前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
4天前
已完结
Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models
4天前
已完结
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+ Acute Myeloid Leukemia (AML)
5天前
已完结
Identification, structure, and agonist design of an androgen membrane receptor
5天前
已完结
A cryptic pocket in CB1 drives peripheral and functional selectivity
8天前
已完结
Targeting both death and paracaspase domains of MALT1 with antisense oligonucleotides overcomes resistance to immune-checkpoint inhibitors
9天前
已完结
Molecular glues and bifunctional compounds: Therapeutic modalities based on induced proximity
9天前
已完结
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