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Lv1
40 积分
2021-04-15 加入
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Using AlphaFold and Experimental Structures for the Prediction of the Structure and Binding Affinities of GPCR Complexes via Induced Fit Docking and Free Energy Perturbation
1个月前
已完结
Therapeutic Potential of MRGPRX2 Inhibitors on Mast Cells
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Structure, function and pharmacology of human itch receptor complexes
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Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update
2个月前
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An approach for the synthesis of carboxylic acid via phenacyl bromides and diethylamine by oxidative C–C bond cleavage
2个月前
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A rapid and accurate method for evaluating the degradation of pan-Akt in cells by PROTACs using NanoLuc luciferase
2个月前
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Discovery of 4-(3-aminopyrrolidinyl)-3-aryl-5-(benzimidazol-2-yl)-pyridines as potent and selective SST5 agonists for the treatment of congenital hyperinsulinism
2个月前
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Exploring key features of selectivity in somatostatin receptors through molecular dynamics simulations
2个月前
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Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors
2个月前
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Inhibition of Mast Cell Degranulation by Novel Small Molecule MRGPRX2 Antagonists
3个月前
已完结
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