Lv68
1720 积分 2023-09-04 加入
Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs
4天前
已完结
先导化合物结构优化策略(七)——肽类分子结构修饰与改造
1个月前
已完结
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
1个月前
已完结
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
2个月前
已完结
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor
2个月前
已完结
Leveraging Advanced In Silico Techniques in Early Drug Discovery: A Study of Potent Small-Molecule YAP-TEAD PPI Disruptors
2个月前
已完结
Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP‐TEAD Protein‐Protein Interaction Inhibitors
2个月前
已完结
The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition
2个月前
已完结
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation
3个月前
已完结
Kelch-like protein 3 in human disease and therapy
3个月前
已完结
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