Lv3
260 积分 2023-11-11 加入
PCNA: a silent housekeeper or a potential therapeutic target?
21天前
已完结
Targeting the “Undruggable”: Small-Molecule Inhibitors of Proliferating Cell Nuclear Antigen (PCNA) in the Spotlight in Cancer Therapy
1个月前
已完结
From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation
1个月前
已完结
Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders
1个月前
已完结
Molecular glue degrader for tumor treatment
1个月前
已完结
Design, Synthesis and Evaluation of Diarylidenyl Piperidone-Ligated Platinum (IV) Complexes as Chemoimmunotherapeutic Agents
1个月前
已完结
Discovery of novel AdipoRon analogues as potent anti-inflammatory agents against nonalcoholic steatohepatitis
1个月前
已完结
Design, synthesis and anti-NASH effect evaluation of novel GFT505 derivatives in vitro and in vivo
1个月前
已完结
Rational Design of a Potent, Selective, and Metabolically Stable CDK9 Inhibitor to Counteract Osimertinib Resistance through Mcl-1 Suppression and Enhanced BRD4 Co-Targeting
2个月前
已完结
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy
3个月前
已完结
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