Lv4
520 积分 2024-09-24 加入
E3 ligase ligand chemistries: from building blocks to protein degraders
11小时前
已完结
Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (S, Se) and Their Azole Derivatives against Chagas Disease
16小时前
已完结
Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer
16小时前
已完结
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy
7天前
已完结
A patent review of SCF E3 ligases inhibitors for cancer：structural design, pharmacological activities and structure–activity relationship
24天前
已完结
Identification of the antidepressive properties of C1, a specific inhibitor of Skp2, in mice
24天前
已完结
Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474
24天前
已完结
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor
1个月前
已完结
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