Lv1
4 积分 2022-02-27 加入
Identification of Highly Selective Orexin 1 Receptor Antagonists Driven by Structure-Based Design
1天前
待确认
Discovery and first-time disclosure of CVN766, an exquisitely selective orexin 1 receptor antagonist
2天前
已完结
Development of Tricyclic 4,5-Dihydro-3H-pyrrolo[2,3-c]quinolin-4-ones as Potent Autotaxin Inhibitors for Pulmonary Fibrosis Treatment In Vivo
3天前
已完结
Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793
3天前
已完结
Biosynthesis and structure assignment of a hydroxylated metabolite of the orexin-1 receptor antagonist JNJ-61393215
3天前
已完结
Structure-Based Discovery of a Series of Novel MAT2a Inhibitors
4天前
已完结
Discovery of Novel Sulfonylurea NLRP3 Inflammasome Inhibitor for the Treatment of Multiple Inflammatory Diseases
4天前
已完结
Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling
10天前
已完结
A Dual PTPN2/PTPN1 Active-Site Inhibitor Promotes Antitumor Immunity
10天前
已完结
Phenotype-Led Identification of IL-10 Upregulators in Human CD4+ T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors
11天前
已完结
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