Lv4
424 积分 2024-11-25 加入
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinsons Disease
2天前
已关闭
Design of Macrocyclic Drugs
3天前
已关闭
Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment
3天前
已完结
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles
3天前
已完结
Decoding replication stress responses through post-translational modifications
14天前
已完结
Bridging the pyridine-pyridazine synthesis gap by skeletal editing
22天前
已完结
Skeletal editing of pyrrolidines by nitrogen-atom insertion
22天前
已完结
Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability
2个月前
已完结
Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer’s Disease
2个月前
已完结
Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility
2个月前
已完结
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