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48 积分 2021-10-19 加入
An efficient copper-catalyzed coupling reaction of pyridin-2-ones with aryl and heterocyclic halides based on Buchwald's protocol
3天前
已完结
Design, Synthesis, and Structure−Activity Relationship Studies of Triazolo-pyrimidine Derivatives as WRN Inhibitors for the Treatment of MSI Tumors
5天前
已完结
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease
5天前
已完结
Understanding cyclic(alkyl)(amino)carbene–copper complex catalysed N–H and O–H bond addition to electron deficient olefins
7天前
已完结
Synthesis of Tricyclic Nitrogen Heterocycles by a Sequence of Palladium-Catalyzed N–H and C(sp3)–H Arylations
7天前
已完结
Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development
8天前
已完结
Insights into Substrate Self-Assisted Activation of Allylic Alcohols Guiding to Mild Allylic Substitution of Tautomerizable Heteroarenes
10天前
已完结
Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy
16天前
已完结
Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono–Mannich Reaction
17天前
已完结
Photoinduced Catalyst-free Difluoromethylation-Cyclization of Indole Derivatives via Electron Donor-acceptor Complexes Under Visible Light
18天前
已完结
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