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190 积分 2022-07-05 加入
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
1天前
已完结
Targeting cancer with small molecule pan-KRAS degraders
1天前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
15天前
已完结
Protein degraders enter the clinic — a new approach to cancer therapy
2个月前
已完结
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor
2个月前
已完结
Enhancing Performance Through Control-Flow Unmerging and Loop Unrolling on GPUs
7个月前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
8个月前
已完结
Changing trends in the development of AAV-based gene therapies: a meta-analysis of past and present therapies
8个月前
已完结
The implications of IDH mutations for cancer development and therapy
10个月前
已完结
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma
11个月前
已完结
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