Lv61
2270 积分 2022-02-16 加入
Designing around Structural Alerts in Drug Discovery
1小时前
已完结
Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement
11天前
已完结
Ligands for cereblon: 2017–2021 patent overview
9个月前
已完结
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease
1年前
已完结
Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist
1年前
已完结
Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies
1年前
已完结
New Generation of sGC Stimulators: Discovery of Imidazo[1,2-a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension
1年前
已完结
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712
1年前
已完结
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2)
1年前
已完结
“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery
1年前
已完结
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