Lv1
96 积分 2025-03-04 加入
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
15小时前
已完结
Design, synthesis, and biological evaluation of cathepsin B cleavage albumin-binding SN38 prodrug in breast cancer
3天前
已完结
Dual-functional antitumor conjugates improving the anti-metastasis effect of combretastatin A4 by targeting tubulin polymerization and matrix metalloproteinases
3天前
已完结
HPMA Polymeric Nanocarriers for Anticancer Drugs with Tumor Microenvironment-Responsive Extracellular Biodegradation and Intracellular Drug Release
3天前
已完结
A Self-Immolative Spacer That Enables Tunable Controlled Release of Phenols under Neutral Conditions
4天前
已完结
Activity-Based Optical Sensing Enabled by Self-Immolative Scaffolds: Monitoring of Release Events by Fluorescence or Chemiluminescence Output
4天前
已完结
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment
4天前
已完结
Self‐Immolative Linkers Literally Bridge Disulfide Chemistry and the Realm of Thiol‐Free Drugs
4天前
已完结
Stability, Kinetic, and Mechanistic Investigation of 1,8-Self-Immolative Cinnamyl Ether Spacers for Controlled Release of Phenols and Generation of Resonance and Inductively Stabilized Methides
4天前
已完结
Discovery of a Natural Ent-Kaurene Diterpenoid Oridonin as an E3 Ligase Recruiter for PROTACs
8天前
已完结
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