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A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2
3天前
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Inhalable pH-responsive charge-reversal polymer-small interfering RNA polyplexes for directed gene therapy of anaplastic lymphoma kinase fusion-positive lung cancer
5天前
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Endothelial-like cancer-associated fibroblasts facilitate pancreatic cancer metastasis via vasculogenic mimicry and paracrine signalling
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Recapitulating hypoxic metabolism in cartilaginous organoids via adaptive cell-matrix interactions enhances histone lactylation and cartilage regeneration
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The Role of Lactate and Lactylation in the Dysregulation of Immune Responses in Psoriasis
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Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma
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Phosphodiesterase 4 (PDE4) and neurological disorders: A promising frontier in neuropharmacology
16天前
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PDE4 inhibition alleviates HMGB1/C1q/C3-mediated excessive phagocytic pruning of synapses by microglia and depressive-like behaviors in mice
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Regulation of urea cycle by reversible high-stoichiometry lysine succinylation
22天前
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Metabolic reprogramming and AMPK activation: Key players in the therapeutic effects of Cooling Blood and Detoxicating Formular on psoriasis
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