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wan
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2024-03-26 加入
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Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair
6天前
已完结
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B
6天前
已完结
Discovery of a Highly Potent PROTAC Degrader of p300/CBP Proteins for the Treatment of Enzalutamide-Resistant Prostate Cancer
6天前
已完结
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9
6天前
已完结
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
1个月前
已完结
Discovery of Novel Non-nucleoside DOT1LR231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy
2个月前
已完结
Discovery of Imidazo[1,2-a]pyrazine Derivatives as Potent ENPP1 Inhibitors
2个月前
已完结
Discovery of Benzo[d]oxazoles as Novel Dual Small-Molecule Inhibitors Targeting PD-1/PD-L1 and VISTA Pathway
2个月前
已完结
Novel ProTide prodrugs of 5-fluoro-2′-deoxyuridine for the treatment of liver cancer
3个月前
已完结
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
7个月前
已完结
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