Lv11
26 积分 2022-11-04 加入
Axial Chirality in the Sotorasib Drug Substance, Part 2: Leveraging a High-Temperature Thermal Racemization to Recycle the Classical Resolution Waste Stream
1小时前
已完结
Axial Chirality in the Sotorasib Drug Substance, Part 1: Development of a Classical Resolution to Prepare an Atropisomerically Pure Sotorasib Intermediate
1小时前
已完结
Practical Synthesis Strategy for NIR-II Cyanine Fluorophores: Laboratory-Scale Development and Structural Characterization of IR 1048
2天前
已完结
Practical Synthesis of Chiral 3-(Hydroxyiminomethyl)adipic Acid, a Key Intermediate of the ROR-γ Inhibitor JTE-151, via Crystallization-Induced Dynamic Resolution
3天前
已完结
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
3天前
已完结
Biocatalytic Oxidative Desymmetrization of the Substituted Pyrrolidine Intermediate of MK-7845: An Investigational Antiviral Therapy for COVID-19
3天前
已完结
Efficient and Scalable Diastereoselective Synthesis of ((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol Hydrochloride
5天前
已完结
SDMA (Synhydrid, Red-Al, Vitride): A Chemoselective and Safe Solution for Reduction Reactions
5天前
已完结
A Chemoenzymatic Synthesis of STING Agonist MK-2118
10天前
已完结
Synthetic approaches and application of representative clinically approved fluorine-enriched anti-cancer medications
13天前
已完结
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