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78 积分 2023-07-14 加入
Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras
17小时前
已完结
Efficient synthesis of imidazo[1,5-a]pyridine sulfonamido derivative as a PARG inhibitor
1个月前
已完结
Drugging p53: Barriers, Criteria, and Prospects
4个月前
已完结
Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia
5个月前
已完结
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor
9个月前
已完结
Computational benchmarking of putative KIFC1 inhibitors
9个月前
已完结
Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy
9个月前
已完结
Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors
9个月前
已完结
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor
9个月前
已完结
DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders
10个月前
已完结
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