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270 积分 2023-11-25 加入
Abstract 3578: A novel and selective 3-phosphoinositide-dependent kinase-1 inhibitor, PF-5177624, blocks insulin-like growth factor-1 induced tumorigenesis in breast cancer cells
1个月前
已关闭
Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1
2个月前
已完结
Structure-based optimization of potent PDK1 inhibitors
2个月前
已完结
For a PDK1 inhibitor, the substrate matters
2个月前
已完结
Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery
2个月前
已完结
Structure-based design of PDK1 inhibitors
2个月前
已完结
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screening
2个月前
已完结
Insilico molecular modelling to identify PDK-1 targeting agents based on its protein–protein docking interaction
2个月前
已完结
Unveiling innovative therapeutic strategies and future trajectories on stimuli-responsive drug delivery systems for targeted treatment of breast carcinoma
4个月前
已完结
The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation
7个月前
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Multifunctional HNT@Fe3O4@PPy@DOX Nanoplatform for Effective Chemo-Photothermal Combination Therapy of Breast Cancer with MR Imaging
8个月前
已采纳
Marine-Derived Secondary Metabolite, Griseusrazin A, Suppresses Inflammation through Heme Oxygenase-1 Induction in Activated RAW264.7 Macrophages
9个月前
已采纳
Unraveling Defect-Mediated Enhancement of Transient Photoconductivity and Slower Carrier’s Mobility Decay in Cu-Doped Cs2AgBiBr6 Nanocrystals Using Ultrafast Pump–Probe Spectroscopy
9个月前
已采纳
Iron Catalyzed Methane Pyrolysis in a Stratified Fluidized Bed Reactor
9个月前
已采纳
Z-Scheme Heterojunction α-Fe2O3/Tubular g-C3N4 with C Defects for Photocatalytic Degradation of Microcystin-LR in Water: Generation and Effect of Critical Species 1O2
9个月前
已采纳
ZScheme Heterojunction Fe2O3/Tubular gC3N4 with C Defects for Photocatalytic Degradation of Microcystin-LR in Water: Generation and Effect of Critical Species 1O2
9个月前
已采纳
1,4-Pd Migration-Enabled Synthesis of Fused 4-Membered Rings
9个月前
已采纳
Metal-Involving Chalcogen Bond. The Case of Platinum(II) Interaction with Se/Te-Based σ-Hole Donors
9个月前
已采纳
One-Step Carbothermal Synthesis of Robust CdS@BPC Photocatalysts in the Presence of Biomass Porous Carbons
9个月前
已采纳
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