Lv22
110 积分 2023-02-03 加入
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
19小时前
待确认
Leveraging Bidirectional Nature of Allostery To Inhibit Protein–Protein Interactions (PPIs): A Case Study of PCSK9–LDLR Interaction
5个月前
已完结
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis
6个月前
已完结
Discovery of Reversible Covalent Bruton’s Tyrosine Kinase Inhibitors PRN473 and PRN1008 (Rilzabrutinib)
6个月前
已完结
Structural Insights into Branch Site Proofreading by Human Spliceosome
6个月前
已完结
Small molecule approaches to targeting RNA
9个月前
已完结
Moving Beyond Active-Site Detection: MixMD Applied to Allosteric Systems
11个月前
已完结
Tuning Stacking Interactions between Asp–Arg Salt Bridges and Heterocyclic Drug Fragments
1年前
已完结
MCPB.py: A Python Based Metal Center Parameter Builder
1年前
已完结
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
1年前
已完结
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