Lv41
448 积分 2023-01-31 加入
Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC
20天前
已完结
Screening assays for tyrosine kinase inhibitors: A review
1个月前
已完结
Targeting Solvent-Front Mutations for Kinase Drug Discovery: From Structural Basis to Design Strategies
1个月前
已完结
Novel Substrate Prediction for the TAM Family of RTKs Using Phosphoproteomics and Structure-Based Modeling
2个月前
已完结
Identification of a novel spirocyclic Nek2 inhibitor using high throughput virtual screening
2个月前
已完结
Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation
2个月前
已完结
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
2个月前
已完结
Discovery of highly potent and selective EGFRT790M/L858R TKIs against NSCLC based on molecular dynamic simulation
2个月前
已完结
Acquired Secondary HER2 Mutations Enhance HER2/MAPK Signaling and Promote Resistance to HER2 Kinase Inhibition in Breast Cancer
2个月前
已完结
Managing side effects: guidance for use of immunotherapies in multiple myeloma
3个月前
已关闭
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