Lv11
40 积分 2023-06-19 加入
EPIC-1042 as a potent PTRF/Cavin1–caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for glioblastoma
1小时前
已完结
268 POLY (ADP-RIBOSE) POLYMERASE 1 (PARP1) PROMOTES THE RELEASE OF HMGB1 INCREASING INTESTINAL INFLAMMATION
2个月前
已完结
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer
2个月前
已完结
Hydrophobic tag tethering degrader as a promising paradigm of protein degradation: Past, present and future perspectives
2个月前
已完结
Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer
2个月前
已完结
Integrative Modeling of PROTAC-Mediated Ternary Complexes
2个月前
已完结
Methods for computer-assisted PROTAC design
2个月前
已完结
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction
2个月前
已完结
Discovery of a potent and selective PARP1 degrader promoting cell cycle arrest via intercepting CDC25C-CDK1 axis for treating triple-negative breast cancer
2个月前
已完结
A PARP1 PROTAC as a novel strategy against PARP inhibitor resistance via promotion of ferroptosis in p53-positive breast cancer
2个月前
已完结
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