Lv3
340 积分 2023-07-26 加入
Drug–Drug Interaction Potential of Marketed Oncology Drugs: In Vitro Assessment of Time-Dependent Cytochrome P450 Inhibition, Reactive Metabolite Formation and Drug–Drug Interaction Prediction
1个月前
已完结
Projections of Drug-Drug Interactions Caused by Time-Dependent Inhibitors of Cytochrome P450 1A2, 2B6, 2C8, 2C9, 2C19, and 2D6 Using In Vitro Data in Static and Dynamic Models
1个月前
已完结
Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
1个月前
已完结
Risk Assessment for Drug-Drug Interaction Caused by Metabolism-Based Inhibition of CYP3A Using Automated in Vitro Assay Systems and Its Application in the Early Drug Discovery Process
2个月前
已完结
Irreversible Enzyme Inhibition Kinetics and Drug–Drug Interactions
3个月前
已关闭
Assessing Cytochrome P450 Time-Dependent Inhibition (IC50 Shift Assay) Using Both Diluted and Non-Diluted Methods
3个月前
已完结
Use of stable isotope labeled probes to facilitate liquid chromatography/mass spectrometry based high‐throughput screening of time‐dependent CYP inhibitors
3个月前
已完结
Kinetic values for mechanism-based enzyme inhibition: Assessing the bias introduced by the conventional experimental protocol
3个月前
已完结
An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes
3个月前
已完结
Effect of Mibefradil on CYP3A4 In Vivo
4个月前
已完结
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