Lv3
368 积分 2024-09-12 加入
Discovery of CN0 as a novel proteolysis-targeting chimera (PROTAC) degrader of PARP1 that can activate the cGAS/STING immunity pathway combined with daunorubicin
7天前
已完结
A PARP1 PROTAC as a novel strategy against PARP inhibitor resistance via promotion of ferroptosis in p53-positive breast cancer
7天前
已完结
Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader
7天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
4个月前
已完结
Discovery of MD-265: A Potent MDM2 Degrader That Achieves Complete Tumor Regression and Improves Long-Term Survival of Mice with Leukemia
4个月前
已完结
Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα)
4个月前
已完结
Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders
4个月前
已完结
Transdermal Drug Delivery Systems and their Potential in Alzheimer’s Disease Management
4个月前
已完结
Bioequivalence and safety comparison of once‐weekly donepezil transdermal system with oral donepezil: results of a phase 1 pharmacokinetic study in healthy volunteers
4个月前
已完结
Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
4个月前
已完结
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