Lv7
5000 积分 2021-09-03 加入
Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB
7天前
已完结
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
13天前
已完结
JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
17天前
已完结
An Oral Interleukin-23–Receptor Antagonist Peptide for Plaque Psoriasis
17天前
已完结
Protein degraders push into novel target space
26天前
已完结
Deuterated Drugs: Isotope Distribution and Impurity Profiles
1个月前
已完结
Insight into Thermodynamic and Kinetic Profiles in Small-Molecule Optimization
1个月前
已完结
In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes
2个月前
已完结
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors
2个月前
已完结
Identification and Characterization of a Blood–Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor
2个月前
已完结
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