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Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)
1个月前
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BCL6 coordinates muscle mass homeostasis with nutritional states
2个月前
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Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor
3个月前
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Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities
3个月前
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3个月前
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4个月前
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Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer
4个月前
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Intestine-Settled Electrospun Short-Fibers Modulate Epithelial Transport Proteins to Reduce Purine and Glucose Uptake
5个月前
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