Lv3
220 积分 2023-07-07 加入
Synthesis of C2-β-Fluoro-Substituted Adenine Nucleosides Via Pivaloyl Derivatives of Adenosine and 3 -Deoxyadenosine
3个月前
已完结
Selective Synthesis of N6,3′,5′-Tripivaloyladenosine via Dynamic Kinetic Crystallization and Regioselective Preparation of Pivalated 2′-Deoxy-2′-fluoroarabinoadenosines
3个月前
已完结
Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity
6个月前
已完结
Abstract 743: Using a novel NextGen linker system to generate a conditionally active biologic (CAB) anti-nectin4-ADC demonstrates improved efficacy in pancreatic PDX cancer models and improved tolerability and toxicity profile in non-human primates
6个月前
已关闭
Nectin-4-directed antibody-drug conjugates (ADCs): Spotlight on preclinical and clinical evidence
6个月前
已完结
Development of a Scalable Route for a Highly Polar Heterocyclic Aminocyclopropyl Building Block
7个月前
已完结
Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239
7个月前
已完结
Commercial Route Development Toward PF-07265807, an AXL-MER Inhibitor Oncology Candidate
7个月前
已完结
Development of a Scalable, Stereoselective Second-Generation Route for CXCR7 Antagonist ACT-1004-1239 via Chiral Enamine Reduction and a Novel Telescoped Sequence of Transesterification, cis-to-trans Epimerization, and Saponification
7个月前
已完结
Development of a Scalable, Racemic First-Generation Route for CXCR7 Antagonist ACT-1004-1239 via cis-to-trans Epimerization and Subsequent Separation of Enantiomers
7个月前
已完结
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