Lv11
80 积分 2020-04-14 加入
Discovery of a Novel Glucagon Receptor Antagonist N-[(4-{(1S)-1-[3-(3, 5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the Treatment of Type II Diabetes
2小时前
待确认
DYRK1A aggravates β cell dysfunction and apoptosis by promoting the phosphorylation and degradation of IRS2
2个月前
已完结
Advances in drug discovery for human beta cell regeneration
2个月前
已关闭
Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions
2个月前
已完结
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system
2个月前
已完结
Discovery of potent small molecule inhibitors of DYRK1A by structure-based virtual screening and bioassay
2个月前
已完结
Function and inhibition of DYRK1A: Emerging roles of treating multiple human diseases
3个月前
已完结
Discovery of ZJCK-6-46: A Potent, Selective, and Orally Available Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor for the Treatment of Alzheimer’s Disease
3个月前
已完结
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
4个月前
已完结
Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
5个月前
已关闭
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