标题 |
A Multicenter, Randomized, Parallel Controlled, trial to Evaluate the Efficacy of Exercise Rehabilitation Therapy on Prognosis and Metabonomics in Heart Failure Patients with Preserved Ejection Fraction
一项评估运动康复治疗对射血分数正常心力衰竭患者预后和代谢组学疗效的多中心、随机、平行对照试验
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其它 |
author:ChiCtr, year:2021 INTERVENTION: Experimental group:Medication+Exercise rehabilitation;Control Group:Medication; CONDITION: Heart failure preserved with ejection fraction PRIMARY OUTCOME: 6‐minute walking test;cardiopulmonary exercise test;NT‐ProBNP;brain natriuretic peptide;cardiac color Doppler examination;eukaryotic reference transcriptome sequencing;targeted metabolomic detection; SECONDARY OUTCOME: Minnesota quality of life scale for cardiac insufficiency;Kansas City Cardiomyopathy Questionnaire;total efficacy assessment; INCLUSION CRITERIA: 1. When signing the informed consent, the subjects must be 40 years old and above; 2. Patients diagnosed with heart failure, NYHA II‐III, mainly due to outpatient consultation or hospitalization of heart failure; 3. LVEF >= 50% measured in any form within the past 12 months |
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