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[高分] BioWorld杂志 AZD-5335, a novel FR-α antibody/TOP1 inhibitor ADC with promising preclinical activity in ovarian cancer models
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AZD-5335, a novel FR-α antibody/TOP1 inhibitor ADC with promising preclinical activity in ovarian cancer models April 17, 2023 Researchers from Astrazeneca plc described the development and preclinical evaluation of AZD-5335, a novel antibody-drug conjugate (ADC) consisting of folate receptor α (FR-α)-targeting antibody conjugated to a proprietary topoisomerase 1 inhibitor (TOP1i), being developed as a potential new therapeutic against ovarian cancer. BioWorld Science |
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