| 标题 |
Long noncoding RNA ATB promotes osteosarcoma cell proliferation, migration and invasion by suppressing miR-200s
相关领域
骨肉瘤
癌症研究
癌变
长非编码RNA
下调和上调
细胞生长
小RNA
转移
基因敲除
转化生长因子
生物
竞争性内源性RNA
细胞周期
细胞迁移
细胞
癌基因
基因沉默
细胞生物学
基因
转染
癌症
遗传学
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| 其它 | Long noncoding RNA activated by transforming growth factor-β (lncRNA-ATB) is a novel lncRNA, which is recently reported to have critical roles in carcinogenesis and progression of several cancers. However, the expression, clinical values, biological roles, and underlying molecular mechanisms of lncRNA-ATB in osteosarcoma are still known. In this study, we measured lncRNA-ATB expression in serum and osteosarcoma tissues of osteosarcoma patients, analyzed its diagnostic and prognostic values. Serum lncRNA-ATB is increased in osteosarcoma patients and could accurately discriminate osteosarcoma patients from healthy controls. LncRNA-ATB is also upregulated in osteosarcoma tissues and cell lines, and positively associated with |
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2021-12-06 14:33:42 发布，悬赏 10 积分
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