| 标题 |
[高分] Treatment of hepatic encephalopathy with rifaximin: Double blind, double dummy study versus lactulose
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| 备注 |
作者：P Massa，E Vallerino，M Dodero
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| 其它 | 摘要：Forty patients (27 males and 13 females) with a mean age of 54.5 years (range 42-60), affected by hepatic encephalopathy, were treated in double blind, double dummy conditions for 15 days with rifaximin (1.2 g/day) or with lactulose (60 g/day) (20 vs. 20 cases). The treatment with rifaximin proved as effective as that with lactulose in controlling the neurological signs and symptoms of hepatic encephalopathy and in reducing the high levels of ammonaemia present at the start of treatment. The therapeutic action of rifaximin appeared however to be preferable, being more rapid and significant. The use of rifaximin is recommended due to its broad spectrum of action on ammonium-producing bacteria and because the antibiotic is not absorbed at a gastrointestinal level. It is also well tolerated, unlike what is observed, to a greater or lesser extent with the use of other preparations employed to treat this disease. |
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巴东郡小吏 在
2021-08-21 20:09:13 发布，悬赏 50 积分
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