已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Talc slurry pleurodesis in patients with secondary intractable pneumothorax: A phase 2 study

医学 胸膜成形术 滑石 气胸 外科 生理盐水 渗出 麻醉 胸膜腔 复合材料 材料科学
作者
Hideo Saka,Masahide Oki,Yoshikane Yamauchi,Chiyoe Kitagawa,Akiko Kada,Akiko Saito,Haruhiko Kondo,Hirotaka Kida,Noriaki Takahashi,Akihiro Bessho,Katsuhiro Okuda,Hideki Miyazawa
出处
期刊:Respiratory investigation [Elsevier]
卷期号:62 (2): 277-283
标识
DOI:10.1016/j.resinv.2024.01.005
摘要

Secondary pneumothorax, which occurs most commonly in the elderly, is caused by underlying diseases. Cardiac dysfunction and other organ inefficiencies may render surgical repair impossible. Such non-operative and poor-risk cases are targets for pleurodesis, which involves the instillation of chemicals or irritants to the thoracic cavity through injection, bronchoscopic bronchial occlusion, or other procedures. Sterile graded talc has been used for pleurodesis mainly in Europe and the United States; however, only a few studies and case series investigating this topic have been published. This study evaluates the efficacy and safety of talc slurry pleurodesis. Patients with inoperable secondary intractable pneumothorax, who were not candidates for surgical repair, were recruited. Four grams of sterilized talc was suspended in 50 mL of physiological saline and injected through a tube into the pleural cavity. Additional 50 mL of saline was subsequently injected through the same channel to clean the residual saline in the injection tube. Another additional talc instillation was allowed to control persistent air leakage. The primary endpoint was the proportion of drainage tube removal within 30 days after talc pleurodesis. Thirty-one patients were included in this study. In 23 out of 28 patients, the drainage tube could be removed within 30 days of talc instillation (82.1 %, 95 % CI = 63.1–93.9), exceeding the threshold of 36.0 % (p < 0.0001). The most common event was pain (11/28 patients, 39.3 %). Talc slurry pleurodesis is effective for intractable secondary pneumothorax, with minor side effects.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
blue2021发布了新的文献求助10
刚刚
1秒前
不可思议发布了新的文献求助10
3秒前
孤芳自赏IrisKing完成签到 ,获得积分10
13秒前
研友_ngX12Z完成签到 ,获得积分10
17秒前
20秒前
20秒前
完美世界应助qiqi1111采纳,获得10
24秒前
冯婷完成签到 ,获得积分10
26秒前
32秒前
32秒前
爱听歌夜南完成签到,获得积分10
35秒前
大胆翎发布了新的文献求助30
36秒前
打打应助洁净伟祺采纳,获得10
36秒前
37秒前
jerry完成签到,获得积分10
37秒前
脑洞疼应助辛勤的冷松采纳,获得10
38秒前
qiqi1111发布了新的文献求助10
38秒前
abiorz完成签到,获得积分10
40秒前
窗外是蔚蓝色完成签到,获得积分10
40秒前
深情安青应助派小星采纳,获得10
55秒前
Billy应助科研通管家采纳,获得10
55秒前
科研通AI2S应助科研通管家采纳,获得10
55秒前
科研通AI2S应助科研通管家采纳,获得10
55秒前
FashionBoy应助科研通管家采纳,获得10
55秒前
科研通AI2S应助科研通管家采纳,获得10
56秒前
来了完成签到 ,获得积分10
58秒前
1分钟前
丘比特应助飞鱼z采纳,获得10
1分钟前
ChemPhys完成签到 ,获得积分10
1分钟前
ChemPhys完成签到 ,获得积分10
1分钟前
嗯哼给开朗的觅海的求助进行了留言
1分钟前
大个应助迷路睫毛采纳,获得10
1分钟前
朵啦诶萌发布了新的文献求助10
1分钟前
嗯哼应助大胆翎采纳,获得60
1分钟前
孤独靖柏发布了新的文献求助10
1分钟前
1分钟前
1分钟前
1分钟前
手术刀完成签到 ,获得积分10
1分钟前
高分求助中
Sustainability in ’Tides Chemistry 2000
Studien zur Ideengeschichte der Gesetzgebung 1000
The ACS Guide to Scholarly Communication 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Handbook of the Mammals of the World – Volume 3: Primates 805
Ethnicities: Media, Health, and Coping 800
Gerard de Lairesse : an artist between stage and studio 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3072519
求助须知:如何正确求助?哪些是违规求助? 2726292
关于积分的说明 7493499
捐赠科研通 2373949
什么是DOI,文献DOI怎么找? 1258844
科研通“疑难数据库(出版商)”最低求助积分说明 610394
版权声明 596983