生物
进化生物学
多元化(营销策略)
选择(遗传算法)
单倍型
钥匙(锁)
遗传建筑学
等位基因
遗传学
基因
表型
生态学
计算机科学
业务
人工智能
营销
作者
Sean Stankowski,Zuzanna B. Zagrodzka,Martin D. Garlovsky,Arka Pal,Daria Shipilina,Diego Garcia Castillo,Alan Le Moan,Erica H. Leder,James Reeve,Kerstin Johannesson,Anja M. Westram,Roger K. Butlin
标识
DOI:10.1101/2023.02.13.528213
摘要
Abstract Key innovations are fundamental to biological diversification, but their genetic architecture is poorly understood. A recent transition from egg-laying to live-bearing in Littorina snails provides the opportunity to study the architecture of an innovation that has evolved repeatedly in animals. Samples do not cluster by reproductive mode in a genome-wide phylogeny, but local genealogical analysis revealed numerous genomic regions where all live-bearers carry the same core haplotype. Associated regions show evidence for live-bearer-specific positive selection, and are enriched for genes that are differentially expressed between egg-laying and live-bearing reproductive systems. Ages of selective sweeps suggest live-bearing alleles accumulated gradually, involving selection at different times in the past. Our results suggest that innovation can have a polygenic basis, and that novel functions can evolve gradually, rather than in a single step.
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