环境卫生
污染
人类健康
空气污染
污染
白内障
医学
环境科学
生物
眼科
生态学
作者
Dan-Lei Yang,Zhen-Ning Zhang,Hai Liu,Zi-Yue Yang,Mi-Mi Liu,Qinxiang Zheng,Wei Chen,Ping Xiang
出处
期刊:Chemosphere
[Elsevier]
日期:2023-01-01
卷期号:311: 137037-137037
被引量:25
标识
DOI:10.1016/j.chemosphere.2022.137037
摘要
People spend a long time indoors, especially young children. The risk of indoor pollution on human health is one of the current hotspots in environmental and public health. The human ocular surface is highly susceptible to indoor environment quality. Epidemiological data have linked human ophthalmological disorders with exposure to indoor pollution. In this review, we summarized the adverse impacts of indoor pollution on the human ocular surface. Several studies demonstrated that indoor contaminants including particulate matter, volatile/semi-volatile organic compounds, heavy metals, and fuel combustion and cigarette smoke exposure were associated with the incidence of human dry eye, conjunctivitis, glaucoma, cataracts, age-related macular degeneration, and keratitis. In addition, toxicological investigations revealed that indoor pollution-induced induced chronic inflammation, oxidative damage, and disruption of tight junctions are the main underlying pathological mechanisms for ocular surface diseases. Taken together, this review may expand the understanding of pollution-induced eye disorder and highlight the importance of reducing associated contaminants to decrease their detrimental effects on human eyes.
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