Chemical studies of Coelopleurum gmelinii (D.C.) Ledeb. I. Constituents of the root.

Two new coumarins (9 and 10) and a new chromone (14), together with eight known coumarins (1-8) and three known chromones (11-13), which were identified by comparison with authentic samples, were isolated from the roots of Coelopleurum gmelinii (D.C.) LEDER (Umbelliferae). The structures of 9, 10 and 14 were established as 6-[(1R, 2S)-1, 3-dihydroxy-2-isovaleryloxy-3-methylbutyl]-7-methoxycoumarin, 6-[(1R, 2S)-2-angeloyloxy-3-β-D-glucosyloxy-1-hydroxy-3-methylbutyl]-7-methoxycoumarin (tert-O-glucosylangelol A) and (S)-7-β-D-glucosyloxymethyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-2, 3-dihydro-5H-furo [3, 2-g] [1] benzopyran-5-one (prim-O-glucosylangelicain), respectively.